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R语言的univariate_cox.r怎么使用

发表于:2025-01-16 作者:千家信息网编辑
千家信息网最后更新 2025年01月16日,这篇文章主要介绍了R语言的univariate_cox.r怎么使用的相关知识,内容详细易懂,操作简单快捷,具有一定借鉴价值,相信大家阅读完这篇R语言的univariate_cox.r怎么使用文章都会有
千家信息网最后更新 2025年01月16日R语言的univariate_cox.r怎么使用

这篇文章主要介绍了R语言的univariate_cox.r怎么使用的相关知识,内容详细易懂,操作简单快捷,具有一定借鉴价值,相信大家阅读完这篇R语言的univariate_cox.r怎么使用文章都会有所收获,下面我们一起来看看吧。

单因素cox回归分析

使用方法:

指定单个变量做cox回归分析,可以是临床数据

$Rscript $scriptdir/univariate_cox.r -husage: /share/nas1/huangls/test/TCGA_immu/scripts/univariate_cox.r       [-h] -i data -t time -e event -v variate [variate ...] [-b blocksize]       [-o outdir] [-p prefix]unvariate cox regressionoptional arguments:  -h, --help            show this help message and exit  -i data, --data data  input data file path[required]  -t time, --time time  set suvival time column name [required]  -e event, --event event                        set event column name must 0 or 1 code format                        [required]  -v variate [variate ...], --variate variate [variate ...]                        variate for cox analysis [required]  -b blocksize, --blocksize blocksize                        Number of variables Parallel to test in each [default                        2]  -o outdir, --outdir outdir                        output file directory [default cwd]  -p prefix, --prefix prefix                        out file name prefix [default cox]

使用举例:

Rscript $scriptdir/univariate_cox.r -i nomogram_metadata.tsv -e EVENT -t TIME \  -v gender  riskScore age_at_index    ajcc_pathologic_stage \  -o univariate_cox \  -p  univariate_cox

参数说明:

-i 输入生存数据与临床数据

barcodeTIMEEVENTFGRCD38ITGALCX3CL1CEACAM21MATKCD79BMMP25
TCGA-B7-A5TK-01A-12R-A36D-31288016.3440886.8677240.26903603.01321.8685362.283423.45319813.72829
TCGA-BR-7959-01A-11R-2343-131010011.9673915.794517.35856626.913532.5719170.8641161.8799573.451148
TCGA-IN-8462-01A-11R-2343-1357205.3508463.1113423.76912520.222380.6108390.5197762.8221921.106563
TCGA-CG-4443-01A-01R-1157-1391201.538020.8629552.3735119.040971.0921270.7603481.9265920.878735
TCGA-KB-A93J-01A-11R-A39E-311124015.2401613.304738.0859114.152953.4835593.1929513.65174210.43186
TCGA-HU-A4H3-01A-21R-A251-3188206.2617612.6751737.0258864.0502710.5841591.0393361.9792142.312993
TCGA-RD-A8MV-01A-11R-A36D-313720027.0741520.1588534.9130934.718214.1131122.61555716.5194617.72674
TCGA-VQ-A91X-01A-12R-A414-3128911.0623410.7520182.3805134.4158150.5181420.2121971.2392030.582114











结果展示:

VariableTermBetaHRHRlowerHRupperP
riskScoreriskScore1.3124753.7153562.3299775.9244683.53E-08
ajcc_pathologic_stageajcc_pathologic_stageStage IV1.4190894.1333531.9438288.7891540.000227
ajcc_pathologic_stageajcc_pathologic_stageStage III0.8551992.3518431.2037484.5949530.012327
age_at_indexage_at_index0.0181241.0182891.0007321.0361540.04111
ajcc_pathologic_stageajcc_pathologic_stageStage II0.5336181.705090.8381573.4687170.140829
gendergendermale0.2178161.2433580.8579621.8018740.249868







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